Human Toll-like receptor 10, TLR10 ELISA Kit | TLR10 elisa kit

Human Toll-like receptor 10, TLR10 ELISA Kit

Cat. Num. AAA165150

• Gene Names: TLR10; CD290
• Reactivity: Human
• Synonyms: Toll-like receptor 10; TLR10; Human Toll-like receptor 10; TLR10 ELISA Kit; TLR10 elisa kit

• Reactivity: Human
• Sequence Length: 811

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.1ng/L - 40ng/L.
• Sensitivity: 0.051ng/L
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TLR10 elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Toll-like Receptor 10 (also known as TLR10) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human TLR10 antibody. TLR10 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human TLR10 Antibody is added and binds to TLR10 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TLR10 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human TLR10. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 67626203
• NCBI GeneID: 81793
• UniProt Accession #: Q9BXR5; Q32MI7; Q32MI8; Q5FWG4; Q6UXL3; A8K7L1; B3Y668; D1CS21; D1CS22
• Molecular Weight: 94,564 Da
• NCBI Official Full Name: TLR10
• NCBI Official Synonym Full Names: toll like receptor 10
• NCBI Official Symbol: TLR10
• NCBI Official Synonym Symbols: CD290
• NCBI Protein Information: toll-like receptor 10
• UniProt Protein Name: Toll-like receptor 10
• Protein Family: Toll-like receptor
• UniProt Gene Name: TLR10

NCBI Description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Uniprot Description

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response ().