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Typical Testing Data/Standard Curve (for reference only)

Human tachykinin 4 (hemokinin) ELISA Kit | TAC4 elisa kit

Human Tachykinin-4, TAC4 ELISA Kit

Gene Names
TAC4; EK; HK1; HK-1; PPT-C
Reactivity
Human
Synonyms
tachykinin 4 (hemokinin); Human Tachykinin-4; TAC4 ELISA Kit; TAC4 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
No cross-reaction with other factors.
Samples
Human serum, plasma or cell culture supernatant
Assay Type
Quantitative Sandwich
Detection Range
10 ng/mL-0.156 ng/mL
Sensitivity
Up to 0.05 ng/mL
Intra-assay Precision
<= 8%
Inter-assay Precision
<= 12%
Preparation and Storage
Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for TAC4 elisa kit
Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Human TAC-4 monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and biotinylated antibodies are added into ELISA plate wells and washed out with PBS or TBS after their respective additions to the wells. Then Avidin-peroxidase conjugates are added to the wells in after. TMB substrate is used for coloration after the enzyme conjugate has already been thoroughly washed out of the wells by PBS or TBS. TMB reacts to form a blue product from the peroxidase activity, and finally turns to yellow after addition of the stop solution (Color Reagent C). The color intensity and quantity of target analyte in the sample are positively correlated.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,305 Da
NCBI Official Full Name
tachykinin-4 isoform beta
NCBI Official Synonym Full Names
tachykinin 4 (hemokinin)
NCBI Official Symbol
TAC4
NCBI Official Synonym Symbols
EK; HK1; HK-1; PPT-C
NCBI Protein Information
tachykinin-4; endokinin; preprotachykinin-C
UniProt Protein Name
Tachykinin-4
Protein Family
UniProt Gene Name
TAC4
UniProt Synonym Gene Names
PPT-C; EKA; EKA/B; EKC
UniProt Entry Name
TKN4_HUMAN

NCBI Description

This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TAC4: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. Belongs to the tachykinin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: extracellular region

Molecular Function: receptor binding

Biological Process: tachykinin signaling pathway; regulation of blood pressure; positive regulation of saliva secretion

Research Articles on TAC4

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Product Notes

The Human TAC4 tac4 (Catalog #AAA2602776) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2602776 ELISA Kit recognizes Human TAC4. It is sometimes possible for the material contained within the vial of "tachykinin 4 (hemokinin), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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