Western Blot (WB)
(TAC4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TAC4 antibody detected the TAC4 protein (arrow).)
Rabbit anti-Human TAC4 Polyclonal Antibody | anti-TAC4 antibody
TAC4 Antibody (C-term)
Western Blot (WB)
(TAC4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TAC4 antibody detected the TAC4 protein (arrow).)
Western Blot (WB)
(TAC4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TAC4 antibody detected the TAC4 protein (arrow).)
neurotransmitter-encoding genes. Tachykinin proteins are cleaved
into small, secreted peptides that activate members of a family of
receptor proteins. The products of this gene preferentially
activate tachykinin receptor 1, and are thought to regulate
peripheral endocrine and paracrine functions including blood
pressure, the immune system, and endocrine gland secretion. The
products of this gene lack a dibasic cleavage site found in other
tachykinin proteins. Consequently, the nature of the cleavage
products generated in vivo remains to be determined. Multiple
transcript variants encoding different isoforms have been found for
this gene.
Tran, A.H., et al. Neuropeptides 43(1):1-12(2009)
Cunningham, S., et al. J. Neuroimmunol. 183 (1-2), 208-213 (2007) :
Page, N.M. Vascul. Pharmacol. 45(4):200-208(2006)
Page, N.M. Cell. Mol. Life Sci. 61(13):1652-1663(2004)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TAC4: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. Belongs to the tachykinin family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q21.33
Cellular Component: extracellular region
Molecular Function: receptor binding
Biological Process: tachykinin signaling pathway; regulation of blood pressure; positive regulation of saliva secretion
Research Articles on TAC4
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Product Notes
The TAC4 tac4 (Catalog #AAA9201548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 85-113. The TAC4 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAC4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TAC4 tac4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAC4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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