Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Orexigenic neuropeptide QRFP (QRFP) Standard Curve.)
Human Orexigenic Neuropeptide QRFP (QRFP) ELISA Kit | QRFP elisa kit
Human Orexigenic Neuropeptide QRFP (QRFP) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Orexigenic neuropeptide QRFP (QRFP) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Orexigenic neuropeptide QRFP (QRFP) Standard Curve.)
Background: P518 functions as a high-affinity ligand of GPR103. Both GPR103 and P518 precursor mRNA exhibited highest expression in brain.The 43-amino acid QRFP peptide, a longer form of the P518 peptide is necessary to exhibit full agonistic activity with GPR103. Intravenous administration QRFP caused release of aldosterone, suggesting that QRFP and GPR103 regulate adrenal function.The deduced 126-amino acid protein contains a putative N-terminal 22-amino acid signal peptide and no transmembrane domain, suggesting that the protein or cleavage products can be secreted. The 26-amino acid P518 peptide sequence is located at the C terminus of the precursor protein. In peripheral tissues, P518 precursor mRNA was detected in prostate, testis, colon, thyroid, parathyroid, coronary artery, and bladder.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]
Uniprot Description
QRFP: Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland. Belongs to the RFamide neuropeptide family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q34.12
Cellular Component: extracellular region
Molecular Function: neuropeptide hormone activity; orexigenic neuropeptide QRFP receptor binding
Biological Process: grooming behavior; neuropeptide signaling pathway; locomotory behavior; positive regulation of blood pressure
Research Articles on QRFP
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Product Notes
The Human QRFP qrfp (Catalog #AAA9714667) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714667 ELISA Kit recognizes Human QRFP. It is sometimes possible for the material contained within the vial of "Orexigenic Neuropeptide QRFP (QRFP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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