Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Modulator of apoptosis 1 (MOAP1) Standard Curve.)
Human Modulator Of Apoptosis 1 (MOAP1) ELISA Kit | MOAP1 elisa kit
Human Modulator Of Apoptosis 1 (MOAP1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Modulator of apoptosis 1 (MOAP1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Modulator of apoptosis 1 (MOAP1) Standard Curve.)
Background: Modulator of apoptosis 1 encoded by MOAP1 was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, MOAP1 has been shown to mediate caspase-dependent apoptosis.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008]
Uniprot Description
MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family.
Chromosomal Location of Human Ortholog: 14q32
Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol
Molecular Function: protein binding; ubiquitin protein ligase binding
Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; positive regulation of apoptosis
Research Articles on MOAP1
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Product Notes
The Human MOAP1 moap1 (Catalog #AAA9715238) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715238 ELISA Kit recognizes Human MOAP1. It is sometimes possible for the material contained within the vial of "Modulator Of Apoptosis 1 (MOAP1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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