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Human MHC Class I Polypeptide Related Sequence B (MICB) ELISA Kit | MICB elisa kit

Human MHC Class I Polypeptide Related Sequence B (MICB) ELISA Kit

Gene Names
MICB; PERB11.2
Reactivity
Human
Synonyms
MHC Class I Polypeptide Related Sequence B (MICB); Human MHC Class I Polypeptide Related Sequence B (MICB) ELISA Kit; MIC-B; PERB11.2; MHC class I chain-related protein B; MICB elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
351
Assay Type
Sandwich
Samples
Serum, Plasma, Tissue Homogenates or Other Biological Fluids
Detection Range
62.5-4000pg/mL
Sensitivity
29pg/mL

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
4,287 Da
NCBI Official Full Name
MHC class I polypeptide-related sequence B isoform 2
NCBI Official Synonym Full Names
MHC class I polypeptide-related sequence B
NCBI Official Symbol
MICB
NCBI Official Synonym Symbols
PERB11.2
NCBI Protein Information
MHC class I polypeptide-related sequence B
UniProt Protein Name
MHC class I polypeptide-related sequence B
UniProt Gene Name
MICB
UniProt Synonym Gene Names
MIC-B

NCBI Description

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Uniprot Description

Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Research Articles on MICB

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Product Notes

The Human MICB micb (Catalog #AAA457251) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA457251 ELISA Kit recognizes Human MICB. It is sometimes possible for the material contained within the vial of "MHC Class I Polypeptide Related Sequence B (MICB), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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