Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Metastasis suppressor protein 1 (MTSS1) Standard Curve.)
Human Metastasis Suppressor Protein 1 (MTSS1) ELISA Kit | MTSS1 elisa kit
Human Metastasis Suppressor Protein 1 (MTSS1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Metastasis suppressor protein 1 (MTSS1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Metastasis suppressor protein 1 (MTSS1) Standard Curve.)
Background: MTSS1 (MTSS1, I-BAR Domain Containing) is a Protein Coding gene. Among its related pathways are Hedgehog Pathway and Cytoskeletal Signaling. GO annotations related to this gene include identical protein binding and actin binding. An important paralog of this gene is MTSS1L. May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.
NCBI and Uniprot Product Information
Uniprot Description
MTSS1: an intracellular protein that binds to actin and cortactin, and possesses tumor suppressor activity. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta. Senses and induces curved membranous curvatures important for cellular polarization, mobilization and endocytosis. May be related to cancer progression or tumor metastasis in a variety of organ sites. Its expression is down-regulated by MiR-135a. Downregulated in prostate cancer. Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood. Belongs to the MTSS1 family. Three isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Adaptor/scaffold; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: ruffle; adherens junction; endocytic vesicle; cytoplasm; actin cytoskeleton
Molecular Function: actin monomer binding; actin filament binding; identical protein binding; protein binding; receptor binding
Biological Process: plasma membrane organization and biogenesis; in utero embryonic development; actin filament polymerization; microspike biogenesis; positive regulation of actin filament bundle formation; cell motility; cell adhesion; actin cytoskeleton organization and biogenesis; bone mineralization; transmembrane receptor protein tyrosine kinase signaling pathway; negative regulation of epithelial cell proliferation
Research Articles on MTSS1
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Product Notes
The Human MTSS1 mtss1 (Catalog #AAA9715137) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715137 ELISA Kit recognizes Human MTSS1. It is sometimes possible for the material contained within the vial of "Metastasis Suppressor Protein 1 (MTSS1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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