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Typical Standard Curve/Testing Data

Human IL-11 ELISA Kit | IL-11 elisa kit

IL-11 (Human) ELISA Kit

Gene Names
IL11; AGIF; IL-11
Reactivity
Human
Synonyms
IL-11; IL-11 (Human) ELISA Kit; IL-11 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
120
Samples
Serum, plasma and cell culture supernatants
Assay Type
Quantitative Sandwich
Detection Range
31.25 - 2000 pg/ml
Sensitivity
< 18.75 pg/ml
Preparation and Storage
Store at 4 degree C for 6 months.

Typical Standard Curve/Testing Data

Typical Standard Curve/Testing Data
Related Product Information for IL-11 elisa kit
Background/Introduction: IL-11 is a cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. IL-11 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human IL-9 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human IL-11 captured from the samples.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,994 Da
NCBI Official Full Name
interleukin-11 isoform 2
NCBI Official Synonym Full Names
interleukin 11
NCBI Official Symbol
IL11
NCBI Official Synonym Symbols
AGIF; IL-11
NCBI Protein Information
interleukin-11
UniProt Protein Name
Interleukin-11
UniProt Gene Name
IL11
UniProt Synonym Gene Names
AGIF

NCBI Description

The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Uniprot Description

IL11: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Belongs to the IL-6 superfamily.

Protein type: Cell cycle regulation; Cytokine; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: cytoplasm; extracellular region

Molecular Function: cytokine activity; growth factor activity; protein binding

Biological Process: cell-cell signaling; negative regulation of hormone secretion; positive regulation of cell proliferation; positive regulation of MAPKKK cascade; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription from RNA polymerase II promoter

Research Articles on IL-11

Similar Products

Product Notes

The Human IL-11 il11 (Catalog #AAA846480) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA846480 ELISA Kit recognizes Human IL-11. It is sometimes possible for the material contained within the vial of "IL-11, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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