Typical Testing Data/Standard Curve (for reference only)
Human Galanin (GAL) ELISA Kit | GAL elisa kit
Human Galanin (GAL) ELISA Kit
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. A monoclonal antibody specific to galanin has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled galanin and unlabeled galanin (Standards or samples) with the pre-coated antibody specific to galanin. After incubation the unbound conjugate is washed off. Next, avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The amount of bound HRP conjugate is reverse proportional to the concentration of galanin in the sample. After addition of the substrate solution, the intensity of color developed is reverse proportional to the concentration of galanin in the sample.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system. [provided by RefSeq, Jul 2015]
Uniprot Description
Galanin: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion. Belongs to the galanin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: cell soma; extracellular region; extracellular space; Golgi apparatus; secretory granule
Molecular Function: galanin receptor activity; neuropeptide hormone activity; protein binding; type 1 galanin receptor binding; type 2 galanin receptor binding; type 3 galanin receptor binding
Biological Process: cAMP-mediated signaling; feeding behavior; G-protein coupled receptor signaling pathway; inflammatory response; insulin secretion; negative regulation of lymphocyte proliferation; nervous system development; neuropeptide signaling pathway; positive regulation of apoptosis; positive regulation of catagen; positive regulation of cortisol secretion; positive regulation of large conductance calcium-activated potassium channel activity; positive regulation of transcription from RNA polymerase II promoter; protein kinase A signaling; regulation of glucocorticoid metabolic process; regulation of receptor activity; response to drug; response to estrogen; response to insulin stimulus
Disease: Epilepsy, Familial Temporal Lobe, 8
Research Articles on GAL
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Product Notes
The Human GAL gal (Catalog #AAA2700462) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2700462 ELISA Kit recognizes Human GAL. It is sometimes possible for the material contained within the vial of "Galanin (GAL), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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