Human G-CSFR ELISA Kit | G-CSFR elisa kit

G-CSFR (Human) OmniKine ELISA Kit

Cat. Num. AAA9501950

• Gene Names: CSF3R; SCN7; CD114; GCSFR
• Reactivity: Human
• Synonyms: G-CSFR; G-CSFR (Human) OmniKine ELISA Kit; Granulocyte colony-stimulating factor receptor; G-CSF receptor; CD114; GCSFR; G-CSFR elisa kit

• Reactivity: Human
• Specificity: The OmniKine Human G-CSFR ELISA is capable of recognizing both recombinant and naturally produced Human G-CSFR proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: G-CSF, GM-CSF Rbeta, M-CSF R/Fc Chimera; Murine: G-CSF
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 836

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 32-2000 pg/ml
• Sensitivity: 32-2000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human G-CSFR ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human G-CSFR proteins within the range of 32-2000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 4503081
• NCBI GeneID: 1441
• NCBI Accession #: NP_000751.1
• NCBI GenBank Nucleotide #: NM_000760.3
• UniProt Accession #: Q99062
• Molecular Weight: 86,609 Da
• NCBI Official Full Name: granulocyte colony-stimulating factor receptor isoform a
• NCBI Official Synonym Full Names: colony stimulating factor 3 receptor
• NCBI Official Symbol: CSF3R
• NCBI Official Synonym Symbols: SCN7; CD114; GCSFR
• NCBI Protein Information: granulocyte colony-stimulating factor receptor
• UniProt Protein Name: Granulocyte colony-stimulating factor receptor
• UniProt Gene Name: CSF3R
• UniProt Synonym Gene Names: GCSFR; G-CSF receptor; G-CSF-R

NCBI Description

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]

Uniprot Description

GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: extracellular region; integral component of plasma membrane; plasma membrane

Molecular Function: granulocyte colony-stimulating factor binding; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity

Biological Process: cell adhesion; cytokine-mediated signaling pathway; defense response; neutrophil chemotaxis; regulation of myeloid cell differentiation; signal transduction

Disease: Neutropenia, Severe Congenital, 7, Autosomal Recessive; Neutrophilia, Hereditary