Western Blot (WB)
(Western Blot (WB) analysis of Mitofilin polyclonal antibody at 1:500 dilutionLane1:MCF-7 cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)
Rabbit Mitofilin Polyclonal Antibody | anti-IMMT antibody
Mitofilin Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
Mitofilin; Polyclonal Antibody; Mitofilin Polyclonal Antibody; Mitochondrial inner membrane protein; Cell proliferation-inducing gene 4/52 protein; p87/89; IMMT; HMP; MINOS2; PIG4; PIG52; anti-IMMT antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Mitofilin polyclonal antibody detects endogenous levels of Mitofilin protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
758
Applicable Applications for anti-IMMT antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human Mitofilin.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of Mitofilin polyclonal antibody at 1:500 dilutionLane1:MCF-7 cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of Mitofilin polyclonal antibody at 1:500 dilutionLane1:MCF-7 cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)
Related Product Information for anti-IMMT antibody
Cristae are highly folded inner mitochondrial membrane compartments that are studded with cytochromes and ATP synthase proteins and function to provide a large surface area upon which cellular respiration can occur. Mitofilin, also known as IMMT, HMP, PIG4 or P87/89, is a 758 amino acid inner mitochondrial membrane protein that is preferentially expressed in heart tissue. Existing as three alternatively spliced isoforms, Mitofilin functions to control mitochondrial cristae morphology, including the formation and organization of cristae junctions and normal tubular cristae. Due to its role in mediating cristae structure and function, Mitofilin is essential for normal mitochondrial function and is, thus, critical to overall cell survival.
NCBI and Uniprot Product Information
Uniprot Description
IMMT: 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p11.2|2
Cellular Component: mitochondrion; membrane; mitochondrial inner membrane; integral to membrane
Molecular Function: protein binding
Biological Process: mitochondrial calcium ion homeostasis; response to cold
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Product Notes
The Mitofilin immt (Catalog #AAA3006700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mitofilin Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mitofilin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the Mitofilin immt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mitofilin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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