Human Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) ELISA Kit | DDR1 elisa kit

Human Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) ELISA Kit

Cat. Num. AAA3803159

• Reactivity: Human
• Synonyms: Epithelial Discoidin Domain-Containing Receptor 1 (DDR1); Human Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) ELISA Kit; DDR1 elisa kit

• Reactivity: Human
• Sequence Length: 909

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 0.5ng/ml-8ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for DDR1 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofDDR1in the sample, This DDR1ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusDDR1concentration. The concentration ofDDR1in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 113865857
• NCBI Accession #: NP_001038967.1
• NCBI GenBank Nucleotide #: NP_001038967.1
• UniProt Accession #: Q7YR43
• NCBI Official Full Name: epithelial discoidin domain-containing receptor 1
• UniProt Protein Name: Epithelial discoidin domain-containing receptor 1
• Protein Family: Epithelial discoidin domain-containing receptor
• UniProt Gene Name: DDR1
• UniProt Synonym Gene Names: EDDR1; Epithelial discoidin domain receptor 1

Uniprot Description

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing ().