Rat Receptor Tyrosine Kinase (RTKS) ELISA Kit | RTKS elisa kit

Rat Receptor Tyrosine Kinase (RTKS) ELISA Kit

Cat. Num. AAA3808298

• Gene Names: ERBB4; HER4; ALS19; p180erbB4
• Reactivity: Rat
• Synonyms: Receptor Tyrosine Kinase (RTKS); Rat Receptor Tyrosine Kinase (RTKS) ELISA Kit; RTKS elisa kit

• Reactivity: Rat
• Sequence Length: 1308

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 0.5ng/ml-8ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for RTKS elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofRTKSin the sample, This RTKSELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusRTKSconcentration. The concentration ofRTKSin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 337360
• NCBI GeneID: 2066
• NCBI Official Full Name: receptor tyrosine kinase
• NCBI Official Synonym Full Names: erb-b2 receptor tyrosine kinase 4
• NCBI Official Symbol: ERBB4
• NCBI Official Synonym Symbols: HER4; ALS19; p180erbB4
• NCBI Protein Information: receptor tyrosine-protein kinase erbB-4

NCBI Description

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]