Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit | CECR1 elisa kit

Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit

Cat. Num. AAA2706919

• Gene Names: ADA2; PAN; ADGF; CECR1; IDGFL; SNEDS
• Reactivity: Human
• Synonyms: Cat Eye Syndrome Chromosome Region; Candidate 1 (CECR1); Human Cat Eye Syndrome Chromosome Region; Candidate 1 (CECR1) ELISA Kit; IDGFL; ADGF; ADA2; Cat Eye Syndrome Critical Region Protein 1; CECR1 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1).; No significant cross-reactivity or interference between Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) and analogues was observed.
• Sequence Length: 270

• Assay Type: Double-antibody Sandwich
• Samples: Serum, Plasma and Other Biological Fluids
• Detection Range: 0.312-20ng/mL
• Sensitivity: < 0.118ng/mL
• Application: Enzyme-linked immunosorbent assay for Antigen Detection.
• Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) were tested 20 times on one plate, respectively.
• Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) were tested on 3 different plates, 8 replicates in each plate.
• CV(%) =: SD/meanX100
• Intra-Assay: CV<10%
• Inter-Assay: CV<12%
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CECR1 elisa kit

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 30704990
• NCBI GeneID: 51816
• UniProt Accession #: Q9NZK5; Q6ICF1; Q86UB6; Q8NCJ2; Q96K41; A8K9H4
• Molecular Weight: 30,668 Da
• NCBI Official Full Name: Cat eye syndrome chromosome region, candidate 1
• NCBI Official Synonym Full Names: adenosine deaminase 2
• NCBI Official Symbol: ADA2
• NCBI Official Synonym Symbols: PAN; ADGF; CECR1; IDGFL; SNEDS
• NCBI Protein Information: adenosine deaminase 2; adenosine deaminase CECR1
• UniProt Protein Name: Adenosine deaminase 2
• Protein Family: Adenosine deaminase
• UniProt Gene Name: ADA2

NCBI Description

This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.