Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MCM10 Polyclonal Antibody at dilution of 1:50(×200))
Rabbit anti-Human, Mouse MCM10 Polyclonal Antibody | anti-MCM10 antibody
MCM10 Polyclonal Antibody
Gene Names
MCM10; CNA43; DNA43; PRO2249
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
MCM10; Polyclonal Antibody; MCM10 Polyclonal Antibody; Minichromosome Maintenance 10 Replication Initiation Factor; Minichromosome Maintenance Complex Component 10; Protein MCM10 Homolog; HsMCM10; MCM10 Minichromosome Maintenance Deficient 10; Homolog Of Yeast MCM10; PRO2249; CNA43; DNA43; anti-MCM10 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.7mg/mL (varies by lot)
Sequence Length
874
Applicable Applications for anti-MCM10 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:35-1:200
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human MCM10
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MCM10 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MCM10 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MCM10 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MCM10 Polyclonal Antibody at dilution of 1:50(×200))
Related Product Information for anti-MCM10 antibody
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein MCM10 homolog isoform 2
NCBI Official Synonym Full Names
minichromosome maintenance 10 replication initiation factor
NCBI Official Symbol
MCM10
NCBI Official Synonym Symbols
CNA43; DNA43; PRO2249
NCBI Protein Information
protein MCM10 homolog
UniProt Protein Name
Protein MCM10 homolog
Protein Family
UniProt Gene Name
MCM10
UniProt Synonym Gene Names
PRO2249; HsMCM10
UniProt Entry Name
MCM10_HUMAN
NCBI Description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Research Articles on MCM10
Similar Products
Product Notes
The MCM10 mcm10 (Catalog #AAA2562062) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCM10 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MCM10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:35-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the MCM10 mcm10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCM10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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