Typical Testing Data/Standard Curve (for reference only)
Human Apelin (APLN) ELISA Kit | APLN elisa kit
Human Apelin (APLN) ELISA Kit
Gene Names
APLN; APEL; XNPEP2
Reactivity
Human
Synonyms
Apelin (APLN); Human Apelin (APLN) ELISA Kit; APLN elisa kit
Reactivity
Human
Sequence Length
77
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for APLN elisa kit
Principle of the Assay: Human Apelin (APLN) ELISA Kit employs a two-site sandwich ELISA to quantitate APLN in samples. An antibody specific for APLN has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any APLN present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human APLN detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of APLN bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: APLN is a critical regulator of the myocardial response to infarction and ischemia. In obese and insulin-resistant mice, plasma apelin concentration after fasting was not modified but, the gene-expression level of the APL/APJ system was augmented in the white adipose tissue and reduced in the brown adipose tissue, liver and in kidneys.
Background/Introduction: APLN is a critical regulator of the myocardial response to infarction and ischemia. In obese and insulin-resistant mice, plasma apelin concentration after fasting was not modified but, the gene-expression level of the APL/APJ system was augmented in the white adipose tissue and reduced in the brown adipose tissue, liver and in kidneys.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]
Research Articles on APLN
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Product Notes
The Human APLN (Catalog #AAA9716389) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716389 ELISA Kit recognizes Human APLN. It is sometimes possible for the material contained within the vial of "Apelin (APLN), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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