Human COVID 19 Spike IgG/IgM Coronavirus Antibody | anti-COVID-19 antibody
SARS-CoV-2 Spike IgG/IgM Antibody (AM043105)(Clone AM043105 (105-43))
ELISA: 0.01-1ug/ml
This antibody has been tested by ELISA and is specific for SARS-CoV-2 Spike protein S1 Subunit of Receptor Binding Domain (RBD).
Testing Data
(SARS-CoV-2 Spike IgG/IgM antibody structure Patient serum IgG was sequenced and expressed as a chimeric full-length human immunoglobulin in mammalian 293 cells. This chimeric antibody contains a heavy chain CH1 that is IgG1 isotype, whereas its CH2/CH3/CH4 regions are IgM isotype. The antibody contains a DYKDDDDK Tag and an 8X His Tag at the C-terminus.)
ELISA (EIA)
(SARS-CoV-2 Spike IgG/IgM Antibody (AM043105) tested by ELISA using SARS Spike protein RBD. SARS-CoV-2 Spike RBD protein was coated onto microtiter plates at 10 ug/mL and then incubated with a dilution series of SARS-CoV-2 Spike IgG/IgM Antibody (clone AM043105). Bound antibodies were detected with anti-human IgM conjugated to horseradish peroxidase (HRP) followed by incubation with HRP Substrate and then measuring the resulting absorbance at 450 nm.)
ELISA (EIA)
(SARS-CoV-2 Spike IgG/IgM Antibody (AM043105) tested by ELISA using SARS Spike protein ECD. SARS-CoV-2 Spike Extracellular Domain (ECD a.a. 14-1213) protein was coated onto microtiter plates at 5 ug/mL and then incubated with a dilution series of SARS-CoV-2 Spike IgG/IgM Antibody (clone AM043105). Bound antibodies were detected with anti-human IgM conjugated to horseradish peroxidase (HRP) followed by incubation with HRP Substrate and then measuring the resulting absorbance at 450 nm.)
Background: COVID-19, which is short for coronavirus disease 2019, is the official name of the respiratory disease caused by infection with the novel coronavirus SARS-CoV-2. The virus that causes COVID-19 was named SARS-CoV-2 because it is a coronavirus genetically similar to, yet distinct from, the virus that caused the severe acute respiratory syndrome (SARS) outbreak in 2003. Studying the details of how this virus replicates and causes the disease will allow scientists and physicians to more rapidly develop fast and accurate methods of detection as well as to deploy therapeutic and vaccine strategies. This antibody was derived from COVID-19 patients who have cleared the virus. Patient serum IgG was sequenced and expressed as a chimeric full-length human immunoglobulin in mammalian 293 cells. This chimeric antibody contains a heavy chain CH1 that is IgG1 isotype, whereas its CH2/CH3/CH4 regions are IgM isotype. The antibody contains a DYKDDDDK Tag and an 8X His-tag at the C-terminus.
NCBI and Uniprot Product Information
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Product Notes
The COVID-19 (Catalog #AAA389543) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The SARS-CoV-2 Spike IgG/IgM Antibody (AM043105)(Clone AM043105 (105-43)) reacts with Virus and may cross-react with other species as described in the data sheet. AAA Biotech's COVID 19 Spike IgG/IgM Coronavirus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Applications Validated: ELISA: 0.01-1ug/ml This antibody has been tested by ELISA and is specific for SARS-CoV-2 Spike protein S1 Subunit of Receptor Binding Domain (RBD). Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Spike IgG/IgM Coronavirus, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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