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Typical Testing Data/Standard Curve (for reference only)

Human Interleukin 19 (IL19) CLIA Kit | IL19 clia kit

Human Interleukin 19 (IL19) CLIA Kit

Gene Names
IL19; MDA1; NG.1; ZMDA1; IL-10C
Reactivity
Human
Synonyms
Interleukin 19 (IL19); Human Interleukin 19 (IL19) CLIA Kit; MDA1; ZMDA1; IL-10C; NG.1; Melanoma Differentiation Associated Protein-Like Protein; IL19 clia kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Interleukin 19 (IL19).
No significant cross-reactivity or interference between Interleukin 19 (IL19) and analogues was observed.
Sequence Length
215
Assay Type
Double-antibody Sandwich
Samples
Serum, Plasma and Other Biological Fluids
Detection Range
1.37-1,000pg/mL
Sensitivity
< 0.63pg/mL
Application
Chemiluminescent immunoassay for Antigen Detection.
Intra-assay Precision (Precision within an assay)
3 samples with low, middle and high level Interleukin 19 (IL19) were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays)
3 samples with low, middle and high level Interleukin 19 (IL19) were tested on 3 different plates, 8 replicates in each plate.
CV(%) =
SD/meanX100
Intra-Assay
CV<10%
Inter-Assay
CV<12%
Preparation and Storage
The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for IL19 clia kit
The microplate provided in this kit has been pre-coated with an antibody specific to Interleukin 19 (IL19). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Interleukin 19 (IL19). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Interleukin 19 (IL19) level in the sample or standard.;
Product Categories/Family for IL19 clia kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
23,079 Da
NCBI Official Full Name
interleukin 19
NCBI Official Synonym Full Names
interleukin 19
NCBI Official Symbol
IL19
NCBI Official Synonym Symbols
MDA1; NG.1; ZMDA1; IL-10C
NCBI Protein Information
interleukin-19
UniProt Protein Name
Interleukin-19
Protein Family
UniProt Gene Name
IL19
UniProt Synonym Gene Names
ZMDA1; IL-19
UniProt Entry Name
IL19_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

IL19: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Belongs to the IL-10 family.

Protein type: Secreted; Cytokine; Secreted, signal peptide; Apoptosis

Chromosomal Location of Human Ortholog: 1q32.2

Cellular Component: extracellular space; extracellular region

Molecular Function: cytokine activity

Biological Process: apoptosis; positive regulation of JAK-STAT cascade; immune response; inflammatory response; signal transduction; interleukin-6 biosynthetic process

Research Articles on IL19

Similar Products

Product Notes

The Human IL19 il19 (Catalog #AAA2001213) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2001213 CLIA Kit recognizes Human IL19. It is sometimes possible for the material contained within the vial of "Interleukin 19 (IL19), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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