SDS-Page
Kallikrein 13 Active Protein | KLK13 active protein
Recombinant Human Kallikrein 13 Protein
Gene Names
KLK13; KLKL4; KLK-L4
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Kallikrein 13; Recombinant Human Kallikrein 13 Protein; Kallikrein-13; Kallikrein-Like Protein 4; KLK-L4; KLK13; KLKL4; KLK13 active protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM MES, 150mM NaCl, 10% Glycerol, pH 5.5.
Sequence Length
277
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fragment
Gly17-Ile262
Fusion Tag
C-6His
Activity
Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (R&D Systems, Catalog # ES011). The specific activity is >200 pmoles/min/mug.(Activation description: The proenzyme needs to be activated by Lysyl-Endopeptidase for an activated form)
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Please minimize freeze-thaw cycles.
SDS-Page
SDS-Page
Related Product Information for KLK13 active protein
Protein Construction: Recombinant Human Kallikrein 13 is produced by our Mammalian expression system and the target gene encoding Gly17-Ile262 is expressed with a 6His tag at the C-terminus.
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 28.0kDa
Actual Protein Molecular Mass: 33kDa
Actual Protein Molecular Mass: 33kDa
NCBI Official Full Name
kallikrein-13 isoform 1
NCBI Official Synonym Full Names
kallikrein related peptidase 13
NCBI Official Symbol
KLK13
NCBI Official Synonym Symbols
KLKL4; KLK-L4
NCBI Protein Information
kallikrein-13
UniProt Protein Name
Kallikrein-13
Protein Family
UniProt Gene Name
KLK13
UniProt Synonym Gene Names
KLKL4; KLK-L4
NCBI Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. [provided by RefSeq, Jan 2017]
Research Articles on KLK13
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Product Notes
The KLK13 klk13 (Catalog #AAA2556732) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Kallikrein 13, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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