Carboxypeptidase M Active Protein | Cpm active protein

Recombinant Mouse Carboxypeptidase M Protein

Cat. Num. AAA2556754

• Gene Names: Cpm; AA589379; 1110060I01Rik; 5730456K23Rik; E030045M14Rik
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Carboxypeptidase M; Recombinant Mouse Carboxypeptidase M Protein; CPM; Cpm active protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
• Sequence Length: 443

• Species: Mouse
• Endotoxin: <1.0 EU per mug as determined by LAL test.
• Fragment: Leu18-Ser423
• Fusion Tag: C-6His
• Activity: Measured by its ability to release Larginine from BenzoylAlaArg, with detection of the arginine amino group by ophthaldialdehyde.The specific activity is >40,000 pmoles/min/mug.
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.; Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

SDS-Page

Related Product Information for Cpm active protein

Protein Construction: Recombinant Mouse carboxypeptidase M is produced by our Mammalian expression system and the target gene encoding Leu18-Ser423 is expressed with a 6His tag at the C-terminus.

Background: Carboxypeptidase M (CPM) belongs to the peptidase M14 family, and exists in cell membrane. The protein binds 1 zinc ion per subunit, and cleavage of C-terminal arginine or lysine residues from polypeptides. CPM specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 189458849
• NCBI GeneID: 70574
• NCBI Accession #: NP_081744.1
• NCBI GenBank Nucleotide #: NM_027468.1
• UniProt Accession #: Q80V42; Q497S5; Q9CYH8
• Molecular Weight: Molecular Mass: 47.5kDa; Actual Protein Molecular Mass: 56kDa
• NCBI Official Full Name: carboxypeptidase M
• NCBI Official Synonym Full Names: carboxypeptidase M
• NCBI Official Symbol: Cpm
• NCBI Official Synonym Symbols: AA589379; 1110060I01Rik; 5730456K23Rik; E030045M14Rik
• NCBI Protein Information: carboxypeptidase M
• UniProt Protein Name: Carboxypeptidase M
• Protein Family: Carboxypeptidase
• UniProt Gene Name: Cpm
• UniProt Synonym Gene Names: CPM

Uniprot Description

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins ().