GPIHBP1 blocking peptide
GPIHBP1 Peptide - C-terminal region
Target Description: Dietary fats are packaged by intestine into triglyceride-rich lipoproteins called chylomicrons. The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LPL: MIM 609708) along the luminal surface of capillaries, mainly in heart, skeletal muscle, and adipose tissue. GPIHBP1 is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Uniprot Description
GPIHBP1: Plays a key role in the lipolytic processing of chylomicrons.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: anchored component of external side of plasma membrane; apical plasma membrane; basolateral plasma membrane; external side of plasma membrane; extracellular region; intracellular; plasma membrane
Molecular Function: high-density lipoprotein particle binding; lipid binding; protein transmembrane transporter activity
Biological Process: C-terminal protein lipidation; cholesterol homeostasis; intracellular protein transport; lipid transport; positive regulation of lipoprotein lipase activity; protein import; protein stabilization; regulation of lipoprotein lipase activity; retinoid metabolic process; transcytosis
Disease: Hyperlipoproteinemia, Type Id
Research Articles on GPIHBP1
Similar Products
Product Notes
The GPIHBP1 gpihbp1 (Catalog #AAA3241326) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The GPIHBP1 Peptide - C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPIHBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GPIHBP1 gpihbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QVTMTCCQSS LCNVPPWQSS RVQDPTGKGA GGPRGSSETV GAALLLNLLA. It is sometimes possible for the material contained within the vial of "GPIHBP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
