Western Blot (WB)
(Western blot analysis of extracts from 293 cells, using HSD17B11 antibody.)
anti-Human HSD17B11 Antibody | anti-HSD17B11 antibody
HSD17B11 Antibody
Gene Names
HSD17B11; DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
HSD17B11; HSD17B11 Antibody; 17-beta-HSD 11; 17-beta-HSD XI; 17-beta-hydroxysteroid dehydrogenase 11; 17betaHSD11; 17betaHSDXI; 17bHSD11; CTCL tumor antigen HD-CL-03; cutaneous T-cell lymphoma-associated antigen HD-CL-03; dehydrogenase/reductase SDR family 8; DHB11; EC 1.1.1.62; estradiol 17-beta-dehydrogenase 11; retinal short-chain dehydrogenase/reductase 2; retSDR2; anti-HSD17B11 antibody
Reactivity
Human
Specificity
HSD17B11 antibody detects endogenous levels of total HSD17B11 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
300
Applicable Applications for anti-HSD17B11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:5000
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human HSD17B11.
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from 293 cells, using HSD17B11 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from 293 cells, using HSD17B11 antibody.)
References
Haeseleer F., Methods Enzymol. 316:372-383(2000). Hartmann T.B., Br. J. Dermatol. 150:252-258(2004). Clark H.F., Genome Res. 13:2265-2270(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,936 Da
NCBI Official Full Name
estradiol 17-beta-dehydrogenase 11
NCBI Official Synonym Full Names
hydroxysteroid 17-beta dehydrogenase 11
NCBI Official Symbol
HSD17B11
NCBI Official Synonym Symbols
DHRS8; PAN1B; RETSDR2; SDR16C2; 17BHSD11; 17-BETA-HSD11; 17-BETA-HSDXI
NCBI Protein Information
estradiol 17-beta-dehydrogenase 11
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 11
Protein Family
UniProt Gene Name
HSD17B11
UniProt Synonym Gene Names
DHRS8; PAN1B; SDR16C2; 17-beta-HSD 11; 17bHSD11; 17betaHSD11; 17-beta-HSD XI; 17betaHSDXI; CTCL-associated antigen HD-CL-03; retSDR2
NCBI Description
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
Uniprot Description
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Research Articles on HSD17B11
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Product Notes
The HSD17B11 hsd17b11 (Catalog #AAA8509855) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The HSD17B11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSD17B11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the HSD17B11 hsd17b11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSD17B11, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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