Structure
Darunavir ethanolate, Inhibitor
Darunavir ethanolate
Purity
>98% (HPLC)
Synonyms
Darunavir ethanolate; TMC-114; UIC-94017; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
HIV
Receptor
WTHIV-1protease
Chemical Name
Carbamic acid, N-[(1S, 2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R, 3aS, 6aR)-hexahydrofuro[2, 3-b]furan-3-yl ester, compd. with ethanol(1:1)
SMILES
CCO.CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
Molecular Formula
C29H43N3O8S
CAS Number
635728-49-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Darunavir ethanolate, inhibitor
A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3nM, IC90 of 9nM; blockes the infectivity and replication of HIV-1 (NL4-3) variants with IC50 of 3-29nM, also potent against multi-PI-resistant clinical HIV-1 variants isolated from patients; used to treat and prevent HIV/AIDS. HIV Infection Approved
Product Categories/Family for Darunavir ethanolate, inhibitor
References
1. Surleraux DL, et al. J Med Chem. 2005 Mar 24; 48 (6):1813-22.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct; 47 (10):3123-9.
3. KingnM, et al. J Virol. 2004 Nov; 78 (21):12012-21.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct; 47 (10):3123-9.
3. KingnM, et al. J Virol. 2004 Nov; 78 (21):12012-21.
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Product Notes
The Darunavir ethanolate (Catalog #AAA3605406) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Darunavir ethanolate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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