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Human Mannosidase Alpha Class 2B Member 1 (MAN2B1) Antibody Pair Kit | MAN2B1 antibody pair kit

Human Mannosidase Alpha Class 2B Member 1 (MAN2B1) Antibody Pair Kit (with Standard)

Gene Names
MAN2B1; MANB; LAMAN
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Mannosidase Alpha Class 2B Member 1 (MAN2B1); Human Mannosidase Alpha Class 2B Member 1 (MAN2B1) Antibody Pair Kit (with Standard); MANB; LAMAN; Lysosomal alpha-mannosidase; Lysosomal acid alpha-mannosidase; Mannosidase alpha-B; MAN2B1 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for MAN2B1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
62.5-4000pg/mL
Standard
Recombinant MAN2B1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for MAN2B1 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
113,616 Da
NCBI Official Full Name
mannosidase, alpha, class 2B, member 1, isoform CRA_a
NCBI Official Synonym Full Names
mannosidase alpha class 2B member 1
NCBI Official Symbol
MAN2B1
NCBI Official Synonym Symbols
MANB; LAMAN
NCBI Protein Information
lysosomal alpha-mannosidase
UniProt Protein Name
Lysosomal alpha-mannosidase
UniProt Gene Name
MAN2B1
UniProt Synonym Gene Names
LAMAN; MANB; Laman

NCBI Description

This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Uniprot Description

Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages.

Research Articles on MAN2B1

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Product Notes

The Human MAN2B1 man2b1 (Catalog #AAA2103889) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2103889 Antibody Pair Kit recognizes Human MAN2B1. AAA Biotech's Mannosidase Alpha Class 2B Member 1 (MAN2B1) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the MAN2B1 man2b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mannosidase Alpha Class 2B Member 1 (MAN2B1), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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