Human Hypoxia Inducible Factor 2 Alpha (HIF2a) Antibody Pair Kit | HIF2a antibody pair kit
Human Hypoxia Inducible Factor 2 Alpha (HIF2a) Antibody Pair Kit (with Standard)
Gene Names
Epas1; HLF; Hif2a; HIF2 alpha; HIF-2 alpha
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Hypoxia Inducible Factor 2 Alpha (HIF2a); Human Hypoxia Inducible Factor 2 Alpha (HIF2a) Antibody Pair Kit (with Standard); EPAS1; HLF; MOP2; PASD2; BHLHE73; Endothelial PAS Domain 1; HIF-1 Alpha-Like Factor; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; HIF2a antibody pair kit
Reactivity
Human
Applicable Applications for HIF2a antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant HIF2a (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for HIF2a antibody pair kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
96,718 Da
NCBI Official Full Name
hypoxia inducible factor 2 alpha
NCBI Official Synonym Full Names
endothelial PAS domain protein 1
NCBI Official Symbol
Epas1
NCBI Official Synonym Symbols
HLF; Hif2a; HIF2 alpha; HIF-2 alpha
NCBI Protein Information
endothelial PAS domain-containing protein 1
UniProt Protein Name
Endothelial PAS domain-containing protein 1
UniProt Gene Name
Epas1
UniProt Synonym Gene Names
Hif2a; EPAS-1; HIF-2-alpha; HIF2-alpha
NCBI Description
activates luciferase activity after transfection [RGD, Feb 2006]
Uniprot Description
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD ().
Research Articles on HIF2a
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Product Notes
The Human HIF2a epas1 (Catalog #AAA2090323) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2090323 Antibody Pair Kit recognizes Human HIF2a. AAA Biotech's Hypoxia Inducible Factor 2 Alpha (HIF2a) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the HIF2a epas1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hypoxia Inducible Factor 2 Alpha (HIF2a), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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