FGF5 active protein
FGF5 protein
Gene Names
FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
Applications
User optimized
Purity
> 95% pure
Synonyms
FGF5; FGF5 protein; FGF-5 protein; Fibroblast Growth Factor-5 protein; FGF 5; FGF 5 protein; Smag-82 protein; FGF-5; HBGF-5 protein; FGF5 active protein
Host
Human
Purity/Purification
> 95% pure
Form/Format
Lyophilized from 2x PBS, pH 7.2. Reconstitute in 2x PBS. Reconstitute in 2x PBS to a concentration of 0.5-1.0 mg/ml.
Sequence
Region of FGF5 protein corresponding to amino acids MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG.
Sequence Length
206
Applicable Applications for FGF5 active protein
User optimized
Protein Type
Recombinant
Biological Significance
FGF5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle.
Bioactivity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is approximately 0.5 ng/ml, corresponding to a specific activity of approximately 2 x 10^6 units/mg.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for FGF5 active protein
Purified recombinant Human FGF5 protein
Product Categories/Family for FGF5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27.6 kDa
NCBI Official Full Name
fibroblast growth factor 4
NCBI Official Synonym Full Names
fibroblast growth factor 4
NCBI Official Symbol
FGF4
NCBI Official Synonym Symbols
HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
NCBI Protein Information
fibroblast growth factor 4
UniProt Protein Name
Fibroblast growth factor 4
Protein Family
UniProt Gene Name
FGF4
UniProt Synonym Gene Names
HST; HSTF1; KS3; FGF-4; HST; HST-1; HSTF-1; HBGF-4
UniProt Entry Name
FGF4_HUMAN
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
Uniprot Description
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.
Research Articles on FGF5
Similar Products
Product Notes
The FGF5 fgf4 (Catalog #AAA538235) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FGF5 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the FGF5 fgf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of FGF5 protein correspond ing to amino acids MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG. It is sometimes possible for the material contained within the vial of "FGF5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
