BD3 active protein
BD3 protein
Gene Names
Defb3; BD-3
Applications
User optimized
Purity
> 98% pure
Synonyms
BD3; BD3 protein; BD-3 protein; BD 3; BD 3 protein; beta-defensin-3 protein; BD-3; BD3 active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Supplied lyophilized with no additives. Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/ml.
Sequence
Region of BD3 protein corresponding to amino acids GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK.
Sequence Length
63
Applicable Applications for BD3 active protein
User optimized
Protein Type
Recombinant
Biological Significance
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Bioactivity
Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E Coli.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for BD3 active protein
Purified recombinant Human BD3 protein
Product Categories/Family for BD3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
3.9 kDa
NCBI Official Full Name
beta-defensin 3
NCBI Official Synonym Full Names
defensin beta 3
NCBI Official Symbol
Defb3
NCBI Official Synonym Symbols
BD-3
NCBI Protein Information
beta-defensin 3
UniProt Protein Name
Beta-defensin 3
UniProt Gene Name
Defb3
UniProt Synonym Gene Names
Bd3; BD-3; mBD-3
UniProt Entry Name
DEFB3_MOUSE
Uniprot Description
Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa.
Research Articles on BD3
Similar Products
Product Notes
The BD3 defb3 (Catalog #AAA538170) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BD3 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the BD3 defb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of BD3 protein correspond ing to amino acids GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK. It is sometimes possible for the material contained within the vial of "BD3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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