Typical Testing Data/Standard Curve (for reference only)
Human High mobility group protein B3 ELISA Kit | HMGB3 elisa kit
Human High mobility group protein B3 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
HMGB3: Binds preferentially single-stranded DNA and unwinds double stranded DNA. Belongs to the HMGB family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: chromosome; cytoplasm; nucleus
Molecular Function: DNA bending activity; double-stranded DNA binding; four-way junction DNA binding; protein binding
Biological Process: DNA geometric change; DNA recombination; innate immune response; multicellular organismal development; negative regulation of cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Disease: Microphthalmia, Syndromic 13
Research Articles on HMGB3
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Product Notes
The Human HMGB3 hmgb3 (Catalog #AAA2887366) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887366 ELISA Kit recognizes Human HMGB3. It is sometimes possible for the material contained within the vial of "High mobility group protein B3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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