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Hepatitis C Virus NS5, aa2322-2423, Genotype 1a Recombinant Protein

Hepatitis C Virus NS5, aa2322-2423, Genotype 1a, Recombinant (HCV)

Applications
ELISA, Western Blot
Purity
Purified
95% (10% PAGE coomassie staining) Purified by immunoaffinity chromatography.
Synonyms
Hepatitis C Virus NS5; aa2322-2423; Genotype 1a; Recombinant (HCV); Genotype 1a recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Purified
95% (10% PAGE coomassie staining) Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 50mM tris, pH 8.0, 5mM EDTA. No preservative added.
Applicable Applications for Hepatitis C Virus NS5, aa2322-2423, Genotype 1a recombinant protein
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Hepatitis C Virus NS5, aa2322-2423, Genotype 1a recombinant protein
Hepatitis C Virus (HCV), NS5, (aa2322-2423), genotype 1a, Recombinant. Contains the HCV NS5 Immunodominant region (aa2322-2423) with GST fusion partner. Immunoreactive with HCV positive sera.

Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000aa. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. NS5A is a ~56kD pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008). NS5B (non-structural protein 5B) is an RNA-dependent RNA polymerase responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication. Hepatitis C virus (HCV) can cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. At present there is no vaccine effective against HCV.
Product Categories/Family for Hepatitis C Virus NS5, aa2322-2423, Genotype 1a recombinant protein

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Product Notes

The Hepatitis C Virus NS5, aa2322-2423, Genotype 1a (Catalog #AAA637480) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Hepatitis C Virus NS5, aa2322-2423, Genotype 1a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the Hepatitis C Virus NS5, aa2322-2423, Genotype 1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatitis C Virus NS5, aa2322-2423, Genotype 1a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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