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SDS-Page (Figure 1. Human FLT3, hFc-His Tag on SDS-PAGE under reducing condition.)

FLT3 protein

Human FLT3 Protein, hFc-His Tag

Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
FLT3; Human FLT3 Protein; hFc-His Tag; Flt-3; Flk-2; STK-1; CD135; FLK2; FLT-3; FLT3 protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5 %-14 % trehalose is added as protectants before lyophilization.
Sequence Positions
FLT3 (Asn27-Ser543)+hFc (Glu99-Ala330)
Species
Human
Vector and Tag
C-Human Fc and 6xHis tag
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)

SDS-Page

(Figure 1. Human FLT3, hFc-His Tag on SDS-PAGE under reducing condition.)

SDS-Page (Figure 1. Human FLT3, hFc-His Tag on SDS-PAGE under reducing condition.)

ELISA (EIA)

(Figure 2. ELISA plate pre-coated by 2ug/ml (100ul/well) Human FLT3LG, mFc-His tagged protein (PME100033) can bind Human FLT3, hFc-His tagged protein (PME100007) in a linear range of 0.128-10.02ng/ml.)

ELISA (EIA) (Figure 2. ELISA plate pre-coated by 2ug/ml (100ul/well) Human FLT3LG, mFc-His tagged protein (PME100033) can bind Human FLT3, hFc-His tagged protein (PME100007) in a linear range of 0.128-10.02ng/ml.)
Related Product Information for FLT3 protein
Flt-3 (Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2 (Fetal liver kinase-2), STK-1 (Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

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Product Notes

The FLT3 (Catalog #AAA8575065) is a Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is FLT3 (Asn27-Ser543)+hFc (Glu99-Ala330). It is sometimes possible for the material contained within the vial of "FLT3, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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