CD7 active protein

CD7 Protein, Mouse, Recombinant (His Tag)

Cat. Num. AAA8122718

• Purity: >94% as determined by SDS-PAGE
• Synonyms: CD7; CD7 Protein; Mouse; Recombinant (His Tag); Mouse CD7 Protein (His Tag); CD7 molecule; CD7 active protein

• Host: HEK293 Cells
• Purity/Purification: >94% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Pro150

• Species: Mouse
• Activity: Measured by its ability to bind biotinylated recombinant human SECTM1 in a functional ELISA.
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Gln 24
• Tag: C-His
• Protein Construction: A DNA sequence encoding the mouse CD7 (NP_033984.1) extracellular domain (Met 1-Pro 150) was fused with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for CD7 active protein

Background: The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein that is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

References

Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

NCBI and Uniprot Product Information

• NCBI GI #: 6806905
• NCBI GeneID: 12516
• NCBI Accession #: NP_033984.1
• NCBI GenBank Nucleotide #: NM_009854.2
• UniProt Accession #: P50283
• Molecular Weight: 23,153 Da
• NCBI Official Full Name: T-cell antigen CD7
• NCBI Official Synonym Full Names: CD7 antigen
• NCBI Official Symbol: Cd7
• NCBI Protein Information: T-cell antigen CD7
• UniProt Protein Name: T-cell antigen CD7
• Protein Family: CD70 antigen
• UniProt Gene Name: Cd7
• UniProt Entry Name: CD7_MOUSE

Uniprot Description

CD7: Not yet known.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Cellular Component: membrane; integral to membrane

Biological Process: immune system process; homeostasis of number of cells within a tissue