Coronavirus Hemagglutinin-esterase Recombinant Protein | HE recombinant protein

Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE)

Cat. Num. AAA8400643

• Purity: >90% by SDS-PAGE
• Synonyms: Coronavirus Hemagglutinin-esterase; Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE); Hemagglutinin-esterase; HE protein; E3 glycoprotein; HE; HE recombinant protein

• Host: Yeast
• Specificity: Structural protein that makes short spikes at the surface of the virus.
• Purity/Purification: >90% by SDS-PAGE
• Form/Format: Lyophilized protein
• Sequence Positions: aa19-424

• Source: Coronavirus
• Tag: N-terminal 6xHis-tag
• Preparation and Storage: Store at -20 degree C; Centrifuge the vial briefly. Reconstitute in deionized sterile water to a concentration of 0.1-1.0mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 degree C/-80 degree C.; Shipping: Gel Pack; Shelf Life: Est.~12 months; Country of Origin: USA

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Related Product Information for HE recombinant protein

Structural protein that makes short spikes at the surface of the virus. It contains receptor binding and receptor-destroying activities and mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps to prevent self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. It seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.

Product Categories/Family for HE recombinant protein

Web Categories; Proteins and Enzymes; Proteins and Enzymes (A-Z); Coronavirus; Proteins; Proteins and Enzymes; Viral Proteins; Infectious Diseases; Microbiology

NCBI and Uniprot Product Information

• NCBI GI #: 122851
• UniProt Accession #: P15776
• Molecular Weight: 47.7 kDa
• NCBI Official Full Name: Hemagglutinin-esterase
• UniProt Protein Name: Hemagglutinin-esterase
• Protein Family: Hemagglutinin-esterase
• UniProt Gene Name: HE
• UniProt Synonym Gene Names: HE protein
• UniProt Entry Name: HEMA_CVBM

Uniprot Description

Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.