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COVID 19 Spike Protein (S1) Coronavirus Recombinant Protein | COVID-19 recombinant protein

Human CellExp SARS-CoV-2 Spike Protein (S1); Recombinant

Purity
>90% by SDS-PAGE
Synonyms
COVID 19 Spike Protein (S1) Coronavirus; Human CellExp SARS-CoV-2 Spike Protein (S1); Recombinant; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike Protein S1; COVID-19 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 cells
Specificity
Glycoprotein that enables viral entry into the host cell
Purity/Purification
>90% by SDS-PAGE
Form/Format
Lyophilized powder
Sequence
Val11-Arg682
Source
Coronavirus
Activity (Specifications/test method)
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human ACE2 at 2ug/mL (100 uL/well) can bind Recombinant SARS-COV-2 Spike S1; the EC50 of SARS-COV-2 Spike S1 is 6.79ng/mL.|Immobilized Human ACE2 on COOH Chip; can bind SARS-COV-2 Spike S1 with an affinity constant of 90.8nM as determined in a SPR assay
Endotoxin Level
< 0.1EU/ug of the protein by LAL method
Tag
Fc, 6×His tag at the C-terminus
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening. Reconstitute to a concentration of 0.1-0.5mg/mL in sterile distilled water.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA

SDS-Page

SDS-Page

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for COVID-19 recombinant protein
SARS-CoV is an enveloped, single, and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. For viral entry, the surface unit (S1) of SARS S binds to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and the transmembrane unit (S2) then fuses the viral membrane with a host cell membrane. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. Because the S protein of SARS-CoV is involved in receptor recognition, as well as virus attachment and entry, it represents one of the most important targets for the development of SARS vaccines and therapeutics.

NCBI and Uniprot Product Information

Molecular Weight
51.5 kDa

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Product Notes

The COVID-19 (Catalog #AAA8400655) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Val11-Arg6 82. It is sometimes possible for the material contained within the vial of "COVID 19 Spike Protein (S1) Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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