Hamster Sodium/Potassium-Transporting Atpase Subunit Alpha-4 (ATP1A4) ELISA Kit | ATP1A4 elisa kit
Hamster Sodium/Potassium-Transporting Atpase Subunit Alpha-4 (ATP1A4) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
ATP1A4: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.3.9; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Transporter; Transporter, ion channel
Chromosomal Location of Human Ortholog: 1q23.2
Cellular Component: integral component of plasma membrane; plasma membrane; sodium:potassium-exchanging ATPase complex
Molecular Function: ATP binding; metal ion binding; sodium:potassium-exchanging ATPase activity
Biological Process: ATP hydrolysis coupled proton transport; establishment or maintenance of transmembrane electrochemical gradient; fertilization; potassium ion transport; regulation of cellular pH; regulation of membrane potential; sodium ion transport; sperm motility; spermatogenesis
Research Articles on ATP1A4
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Product Notes
The Hamster ATP1A4 atp1a4 (Catalog #AAA9901601) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9901601 ELISA Kit recognizes Hamster ATP1A4. It is sometimes possible for the material contained within the vial of "Sodium/Potassium-Transporting Atpase Subunit Alpha-4 (ATP1A4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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