Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using PTGES2 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit PTGES2 Polyclonal Antibody | anti-PTGES2 antibody
PTGES2 Antibody
Predicted: Pig, Bovine, Horse, Dog
Predicted: Pig, Bovine, Horse, Dog
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using PTGES2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using PTGES2 Antibody. The lane on the left was treated with blocking peptide.)
Subunit Structure: Homodimer. May interact with CEBPB (By similarity). Interacts with EXOSC10.
Similarity: Belongs to the GST superfamily.
NCBI and Uniprot Product Information
Predicted: 42 kDa
NCBI Description
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
Uniprot Description
PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily.
Protein type: Lipid Metabolism - arachidonic acid; Isomerase; Membrane protein, integral; EC 5.3.99.3
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus
Molecular Function: electron carrier activity; DNA binding; glutathione binding; lyase activity; protein disulfide oxidoreductase activity; heme binding; prostaglandin-E synthase activity
Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process
Research Articles on PTGES2
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Product Notes
The PTGES2 ptges2 (Catalog #AAA9611463) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGES2 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's PTGES2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PTGES2 ptges2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGES2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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