Rabbit Hyaluronate binding protein ELISA Kit | HABP elisa kit

Rabbit Hyaluronate binding protein ELISA Kit

Cat. Num. AAA726488

• Gene Names: TNFAIP6; TSG6; TSG-6
• Reactivity: Rabbit
• Synonyms: Hyaluronate binding protein; Rabbit Hyaluronate binding protein ELISA Kit; Hyaluronate binding protein (Rabbit); HABP elisa kit

• Reactivity: Rabbit

• Preparation and Storage: Store all reagents at 2-8 degree C

Product Categories/Family for HABP elisa kit

Rabbit ELISA Kit

NCBI and Uniprot Product Information

• NCBI GI #: 26051243
• NCBI GeneID: 7130
• NCBI Accession #: NP_009046.2
• NCBI GenBank Nucleotide #: NM_007115.3
• UniProt Accession #: P98066; Q53TI7; Q8WWI9
• Molecular Weight: 31,203 Da
• NCBI Official Full Name: tumor necrosis factor-inducible gene 6 protein
• NCBI Official Synonym Full Names: tumor necrosis factor, alpha-induced protein 6
• NCBI Official Symbol: TNFAIP6
• NCBI Official Synonym Symbols: TSG6; TSG-6
• NCBI Protein Information: tumor necrosis factor-inducible gene 6 protein; TNF alpha-induced protein 6; hyaluronate-binding protein; TNF-stimulated gene 6 protein; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor-stimulated gene-6 protein
• UniProt Protein Name: Tumor necrosis factor-inducible gene 6 protein
• UniProt Gene Name: TNFAIP6
• UniProt Synonym Gene Names: TSG6; TSG-6
• UniProt Entry Name: TSG6_HUMAN

NCBI Description

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]

Uniprot Description

Function: Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.

Subunit structure: Interacts with inter-alpha-inhibitor (I-alpha-I). Chondroitin sulfate may be required for the stability of the complex. Ref.6

Tissue specificity: Found in the synovial fluid of patients with rheumatoid arthritis. Ref.6

Induction: By TNF.

Sequence similarities: Contains 1 CUB domain.Contains 1 Link domain.