Guinea Pig Structural maintenance of chromosomes protein 2 (SMC2) ELISA Kit | SMC2 elisa kit
Guinea pig Structural maintenance of chromosomes protein 2 (SMC2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010]
Uniprot Description
SMC2L1: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Forms an heterodimer with SMC4. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG. Belongs to the SMC family. SMC2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 9q31.1
Cellular Component: nucleoplasm; nuclear chromosome; cytoplasm; condensin complex; condensed chromosome; cytosol; nucleus
Molecular Function: protein binding; protein heterodimerization activity; ATP binding
Biological Process: meiotic chromosome condensation; mitotic chromosome condensation; cell division; mitotic cell cycle; meiotic chromosome segregation; kinetochore organization and biogenesis
Research Articles on SMC2
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Product Notes
The Guinea Pig SMC2 smc2 (Catalog #AAA7249894) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7249894 ELISA Kit recognizes Guinea Pig SMC2. It is sometimes possible for the material contained within the vial of "Structural maintenance of chromosomes protein 2 (SMC2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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