Immunohistochemistry (IHC)
(Anti-RAPGEF3 / EPAC antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Rabbit RAPGEF3 / EPAC Polyclonal Antibody | anti-RAPGEF3 / EPAC antibody
Anti-RAPGEF3 / EPAC Antibody (N-Terminus) IHC-plus
IHC-P (5 ug/ml)
WB (1 ug/ml)
Long term aliquot and store at -20 degree C
Avoid freeze thaw cycles. Store undiluted.
Immunohistochemistry (IHC)
(Anti-RAPGEF3 / EPAC antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-RAPGEF3 / EPAC antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of EPAC1 in rat brain tissue with EPAC1 antibody at 20 µg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of EPAC1 in rat brain tissue with EPAC1 antibody at 20 µg/mL.)
Western Blot (WB)
(Western blot analysis of EPAC1 in rat skeletal muscle tissue lysate with EPAC1 antibody at 1 ug/ml.)
Western Blot (WB)
(Western blot analysis of EPAC1 in rat skeletal muscle tissue lysate with EPAC1 antibody at 1 ug/ml.)
NCBI and Uniprot Product Information
Uniprot Description
Epac1: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs, misc.; GEFs
Chromosomal Location of Human Ortholog: 12q13.1
Cellular Component: apical part of cell; basal plasma membrane; brush border membrane; cell soma; cortical actin cytoskeleton; endomembrane system; filopodium; growth cone; lamellipodium; membrane; microvillus; perinuclear region of cytoplasm; plasma membrane
Molecular Function: cAMP binding; guanyl-nucleotide exchange factor activity; protein binding; protein domain specific binding; Rap guanyl-nucleotide exchange factor activity
Biological Process: angiogenesis; blood coagulation; brain development; cAMP-mediated signaling; cell proliferation; energy reserve metabolic process; negative regulation of collagen biosynthetic process; platelet activation; positive regulation of angiogenesis; positive regulation of cAMP catabolic process; positive regulation of cell size; positive regulation of GTPase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein export from nucleus; positive regulation of smooth muscle cell migration; positive regulation of stress fiber formation; positive regulation of syncytium formation by plasma membrane fusion; positive regulation of transcription from RNA polymerase II promoter; Rap protein signal transduction; regulation of insulin secretion; response to nicotine; signal transduction; spinal cord development
Research Articles on RAPGEF3 / EPAC
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Product Notes
The RAPGEF3 / EPAC rapgef3 (Catalog #AAA249823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RAPGEF3 / EPAC Antibody (N-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAPGEF3 / EPAC can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (5 ug/ml) WB (1 ug/ml). Researchers should empirically determine the suitability of the RAPGEF3 / EPAC rapgef3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAPGEF3 / EPAC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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