Guinea Pig Cleavage and polyadenylation specificity factor subunit 2 (CPSF2) ELISA Kit | CPSF2 elisa kit
Guinea pig Cleavage and polyadenylation specificity factor subunit 2 (CPSF2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CPSF2: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
Protein type: RNA splicing
Chromosomal Location of Human Ortholog: 14q31.1
Cellular Component: nucleoplasm; membrane; mRNA cleavage and polyadenylation specificity factor complex
Molecular Function: protein binding; RNA binding
Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA export from nucleus; RNA splicing; histone mRNA 3'-end processing; mRNA polyadenylation; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; mRNA cleavage