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Testing Data

Rabbit CPSF2 Polyclonal Antibody | anti-CPSF2 antibody

CPSF2 Antibody

Gene Names
CPSF2; CPSF100
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CPSF2; Polyclonal Antibody; CPSF2 Antibody; CPSF100; KIAA1367; anti-CPSF2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
782
Applicable Applications for anti-CPSF2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000-1:10000
IHC: 1:50-1:200
Immunogen
Fusion protein of CPSF2
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26658 / sc-26659
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88,487 Da
NCBI Official Full Name
cleavage and polyadenylation specificity factor subunit 2
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 2, 100kDa
NCBI Official Symbol
CPSF2
NCBI Official Synonym Symbols
CPSF100
NCBI Protein Information
cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; CPSF 100kDa subunit; cleavage and polyadenylation specificity factor 100 kDa subunit
UniProt Protein Name
Cleavage and polyadenylation specificity factor subunit 2
UniProt Gene Name
CPSF2
UniProt Synonym Gene Names
CPSF100; KIAA1367; CPSF 100 kDa subunit
UniProt Entry Name
CPSF2_HUMAN

Uniprot Description

CPSF2: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.

Protein type: RNA splicing

Chromosomal Location of Human Ortholog: 14q31.1

Cellular Component: nucleoplasm; membrane; mRNA cleavage and polyadenylation specificity factor complex

Molecular Function: protein binding; RNA binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; RNA splicing; mRNA polyadenylation; histone mRNA 3'-end processing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription; mRNA cleavage

Research Articles on CPSF2

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Product Notes

The CPSF2 cpsf2 (Catalog #AAA2524779) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPSF2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CPSF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000-1:10000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CPSF2 cpsf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPSF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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