Human G1 to S phase transition 2 ELISA Kit | GSPT2 elisa kit
Human Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, GSPT2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010]
Uniprot Description
GSPT2: Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Belongs to the GTP-binding elongation factor family. ERF3 subfamily.
Protein type: Hydrolase; RNA-binding; Translation
Chromosomal Location of Human Ortholog: Xp11.22
Cellular Component: cytosol
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: cellular protein metabolic process; translation; mRNA catabolic process, nonsense-mediated decay; gene expression; translational termination; cell cycle
Research Articles on GSPT2
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Product Notes
The Human GSPT2 gspt2 (Catalog #AAA9334247) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334247 ELISA Kit recognizes Human GSPT2. It is sometimes possible for the material contained within the vial of "G1 to S phase transition 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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