Western Blot (WB)
(Mouse p27Kip1 Antibody (C-term T197) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the (mouse) p27Kip1 antibody detected the (mouse) p27Kip1 protein (arrow).)
Rabbit anti-Mouse p27Kip1 Polyclonal Antibody | anti-Cdkn1b antibody
Mouse p27Kip1 Antibody (C-term T197)
Western Blot (WB)
(Mouse p27Kip1 Antibody (C-term T197) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the (mouse) p27Kip1 antibody detected the (mouse) p27Kip1 protein (arrow).)
Western Blot (WB)
(Mouse p27Kip1 Antibody (C-term T197) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the (mouse) p27Kip1 antibody detected the (mouse) p27Kip1 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
p27Kip1: a cell-cycle regulatory protein that Interacts with cyclin-CDK2 and -CDK4, inhibiting cell cycle progression at G1. May mediate TGF beta-induced g1 arrest. Its degradation is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Protein type: Cell cycle regulation; Protein kinase, regulatory subunit; Oncoprotein; Inhibitor
Cellular Component: protein complex; cytoplasm; cytosol; nucleus; endosome
Molecular Function: cyclin-dependent protein kinase inhibitor activity; protein binding; protein kinase inhibitor activity; chaperone binding; protein complex binding; Hsp70 protein binding; caspase activator activity; protein phosphatase binding
Biological Process: caspase activation; cell death; negative regulation of kinase activity; positive regulation of microtubule polymerization; negative regulation of cyclin-dependent protein kinase activity; negative regulation of cell motility; cell cycle; regulation of cell proliferation; negative regulation of cell proliferation; sensory perception of sound; positive regulation of cell proliferation; autophagic cell death; negative regulation of phosphorylation; negative regulation of mitotic cell cycle; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; cell cycle arrest; inner ear development; potassium ion transport; negative regulation of epithelial cell proliferation; negative regulation of apoptosis; G1/S transition of mitotic cell cycle
Research Articles on Cdkn1b
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Product Notes
The Cdkn1b cdkn1b (Catalog #AAA9200909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 175-197. The Mouse p27Kip1 Antibody (C-term T197) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's p27Kip1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Cdkn1b cdkn1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p27Kip1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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