Typical Testing Data/Standard Curve (for reference only)

Mouse Glutamic Pyruvic Transaminase ELISA Kit | GPI/ALT elisa kit

Mouse Glutamic Pyruvic Transaminase ELISA Kit

Gene Names

GPT; AAT1; ALT1; GPT1

Reactivity

Mouse

Synonyms

Glutamic Pyruvic Transaminase; Mouse Glutamic Pyruvic Transaminase ELISA Kit; GPI/ALT elisa kit

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Cat. Num. AAA729344 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Mouse

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Assay Type

Competitive

Detection Range

5.0-100ug/L

Sensitivity

1.0 ug/L

Highest Standards

100ug/L

Concentration of Standards

Preparation and Storage

Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #

4885351

NCBI GeneID

2875

NCBI Accession #

NP_005300.1

NCBI GenBank Nucleotide #

NM_005309.2

Molecular Weight

54,637 Da

NCBI Official Full Name

alanine aminotransferase 1

NCBI Official Synonym Full Names

glutamic-pyruvate transaminase (alanine aminotransferase)

NCBI Official Symbol

GPT

NCBI Official Synonym Symbols

AAT1; ALT1; GPT1

NCBI Protein Information

alanine aminotransferase 1; GPT 1; glutamic-alanine transaminase 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1

UniProt Protein Name

Alanine aminotransferase 1

UniProt Gene Name

GPT

UniProt Synonym Gene Names

AAT1; GPT1; ALT1; GPT 1

UniProt Entry Name

ALAT1_HUMAN

NCBI Description

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]

Uniprot Description

GPT: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Transferase; EC 2.6.1.2

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytosol

Molecular Function: alanine transaminase activity; pyridoxal phosphate binding

Biological Process: amino acid biosynthetic process; L-alanine catabolic process

Research Articles on GPI/ALT

1. A new model that combines ALT, platelets, CK-18 fragments, and triglycerides was established by logistic regression among nonalcoholic fatty liver disease patients.

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Product Notes

The Mouse GPI/ALT gpt (Catalog #AAA729344) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA729344 ELISA Kit recognizes Mouse GPI/ALT. It is sometimes possible for the material contained within the vial of "Glutamic Pyruvic Transaminase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse Glutamic Pyruvic Transaminase ELISA Kit | GPI/ALT elisa kit