Connexin 37 Recombinant Protein | CX37 recombinant protein

Recombinant Connexin 37 (CX37)

Cat. Num. AAA2030246

• Gene Names: GJA4; CX37
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Connexin 37; Recombinant Connexin 37 (CX37); CX37 recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >90%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.; TV VGKIWLTVLF IFRILILGLA GESVWGDEQS DFECNTAQPG CTNVCYDQAF PISHIRYWVL QFLFVSTPTL IYLGHVIYLS RREERLRQKE GELRALPSKD LHVERALAAI EHQMAKISVA EDGRLRIRGA LMGTYVVSVL CKSVLEAGFL YGQWRLYGWT MEPVFVCQRA PCPHIVDCYVSRPTEKTIFI IFMLVVGVIS LVLNLLELVH LLCRCVSREI KARRD
• Sequence Length: 333

• Applicable Applications for CX37 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 56.0KDa
• Accurate Molecular Mass (KD): 56kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: two N-terminal Tags, His-tag and GST-tag
• Organism Species: Mus musculus (Mouse)
• Fragment: Thr19~Asp245
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 7416865
• NCBI GeneID: 2701
• Molecular Weight: 37,414 Da
• NCBI Official Full Name: connexin 37
• NCBI Official Synonym Full Names: gap junction protein, alpha 4, 37kDa
• NCBI Official Symbol: GJA4
• NCBI Official Synonym Symbols: CX37
• NCBI Protein Information: gap junction alpha-4 protein
• UniProt Protein Name: Gap junction alpha-4 protein
• UniProt Gene Name: GJA4
• UniProt Synonym Gene Names: Cx37
• UniProt Entry Name: CXA4_HUMAN

NCBI Description

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008]

Uniprot Description

GJA4: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily.

Protein type: Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: connexon complex; integral to plasma membrane; gap junction

Molecular Function: protein binding

Biological Process: intercellular junction assembly; blood vessel development; cell-cell signaling; transport; calcium ion transport; response to pain