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Testing Data

BMP-3b/GDF-10 Recombinant Protein | GDF10 recombinant protein

BMP-3b / GDF-10, human recombinant

Gene Names
GDF10; BMP3B; BMP-3b
Applications
SDS-Page
Purity
>=95%
Synonyms
BMP-3b/GDF-10; BMP-3b / GDF-10; human recombinant; BMP-3b; BMP3B; BIP; Growth differentiation factor 10; GDF10 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>=95%
Form/Format
1 mg/ml in 10 mM sodium citrate (pH 3.5) containing 10% glycerol
Appearance: Liquid
Concentration
1 mg/ml (varies by lot)
Sequence
MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
Sequence Length
478
Applicable Applications for GDF10 recombinant protein
SDS-PAGE
Endotoxin Level
< 1.0 EU per 1 microgram of protein
Handling
Centrifuge the vial prior to opening.
Preparation and Storage
At -80 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for GDF10 recombinant protein
Background: GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12.5 kDa (111 aa, 369-478 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
growth/differentiation factor 10
NCBI Official Synonym Full Names
growth differentiation factor 10
NCBI Official Symbol
GDF10
NCBI Official Synonym Symbols
BMP3B; BMP-3b
NCBI Protein Information
growth/differentiation factor 10
UniProt Protein Name
Growth/differentiation factor 10
UniProt Gene Name
GDF10
UniProt Synonym Gene Names
GDF-10; BMP-3B; BIP
UniProt Entry Name
GDF10_HUMAN

NCBI Description

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

GDF10: is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that plays a role in skeletal morphogenesis. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10q11.22

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; fat cell differentiation; regulation of MAPKKK cascade; transforming growth factor beta receptor signaling pathway; skeletal development; cell development; growth

Research Articles on GDF10

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Product Notes

The GDF10 gdf10 (Catalog #AAA844679) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BMP-3b/GDF-10 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the GDF10 gdf10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R. It is sometimes possible for the material contained within the vial of "BMP-3b/GDF-10, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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