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Glutamyl-TRNA Amidotransferase Recombinant Protein | GATC recombinant protein

Recombinant Human Glutamyl-TRNA Amidotransferase, Subunit C

Gene Names
GATC; 15E1.2
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Glutamyl-TRNA Amidotransferase; Recombinant Human Glutamyl-TRNA Amidotransferase; Subunit C; GATC Human; Subunit C Human Recombinant; Glutamyl-TRNA(Gln) Amidotransferase Subunit C; Glu-AdT Subunit C; 15E1.2; Glutamyl-TRNA(Gln) Amidotransferase Subunit C Homolog (Bacterial); Glutamyl-TRNA(Gln) Amidotransferase Subunit C Mitochondrial; Glutamyl-TRNA(Gln) Amidotransferase Subunit C Homolog; EC 6.3.5; Protein 15E1.2; GATC recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
GATC protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMWSRLVW LGLRAPLGGR QGFTSKADPQ GSGRITAAVI EHLERLALVDFGSREAVARL EKAIAFADRL RAVDTDGVEP MESVLEDRCL YLRSDNVVEG NCADELLQNS HRVVEEYFVAPPGNISLPKL DEQEPFPHS
Sequence Length
136
Related Product Information for GATC recombinant protein
Description: GATC Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 159 amino acids (1-136 a.a) and having a molecular mass of 17.5kDa (Molecular size on SDS-PAGE will appear higher).GATC is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Glutamyl-TRNA Amidotransferase, Subunit C also known as GATC allows the formation of properly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction occurs in the attendance of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). In addition, GATC is subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (PET112) and C (GATC) subunits.
Product Categories/Family for GATC recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,086 Da
NCBI Official Full Name
glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
NCBI Official Synonym Full Names
glutamyl-tRNA(Gln) amidotransferase, subunit C
NCBI Official Symbol
GATC
NCBI Official Synonym Symbols
15E1.2
NCBI Protein Information
glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; GATC; glu-AdT subunit C; glutamyl-tRNA(Gln) amidotransferase, subunit C homolog
UniProt Protein Name
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
UniProt Gene Name
GATC
UniProt Entry Name
GATC_HUMAN

Uniprot Description

GATC: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). Belongs to the GatC family.

Protein type: EC 6.3.5.-; Mitochondrial

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: mitochondrion

Molecular Function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; ATP binding

Biological Process: mitochondrial translation; regulation of translational fidelity

Research Articles on GATC

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Product Notes

The GATC gatc (Catalog #AAA146216) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMWS RLVW LGLRAPLGGR QGFTSKADPQ GSGRITAAVI EHLERLALVD FGSREAVARL EKAIAFADRL RAVDTDGVEP MESVLEDRCL YLRSDNVVEG NCADELLQNS HRVVEEYFVA PPGNISLPKL DEQEPFPHS. It is sometimes possible for the material contained within the vial of "Glutamyl-TRNA Amidotransferase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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