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GLT11 Blocking Peptide | GALNT11 blocking peptide

GLT11 Antibody (N-term) Blocking Peptide

Gene Names
GALNT11; GALNACT11; GALNAC-T11
Synonyms
GLT11; GLT11 Antibody (N-term) Blocking Peptide; Polypeptide N-acetylgalactosaminyltransferase 11; Polypeptide GalNAc transferase 11; GalNAc-T11; pp-GaNTase 11; Protein-UDP acetylgalactosaminyltransferase 11; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11; GALNT11; GALNT11 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
608
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for GALNT11 blocking peptide
Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N- acetylgalactosaminyltransferases catalyze the transfer of an N- acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
23,090 Da
NCBI Official Full Name
Polypeptide N-acetylgalactosaminyltransferase 11
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 11
NCBI Official Symbol
GALNT11
NCBI Official Synonym Symbols
GALNACT11; GALNAC-T11
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 11
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 11
UniProt Gene Name
GALNT11
UniProt Synonym Gene Names
GalNAc-T11; pp-GaNTase 11
UniProt Entry Name
GLT11_HUMAN

Uniprot Description

GALNT11: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.4.1.41; Transferase; Membrane protein, integral; Glycan Metabolism - O-glycan biosynthesis

Chromosomal Location of Human Ortholog: 7q36.1|7q36.1

Cellular Component: Golgi membrane

Molecular Function: Notch binding; polypeptide N-acetylgalactosaminyltransferase activity

Biological Process: determination of left/right symmetry; Notch receptor processing; O-glycan processing; protein amino acid O-linked glycosylation via threonine; regulation of Notch signaling pathway

Research Articles on GALNT11

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Product Notes

The GALNT11 galnt11 (Catalog #AAA9223042) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GLT11, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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