Western Blot (WB)
(Western Blot analysis of QPRT expression in transfected 293T cell line by QPRT polyclonal antibody. Lane 1: QPRT transfected lysate (32.67kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human QPRT Polyclonal Antibody | anti-QPRT antibody
QPRT (Nicotinate-nucleotide Pyrophosphorylase [Carboxylating], Quinolinate Phosphoribosyltransferase [Decarboxylating]) (AP)
Gene Names
QPRT; QPRTase; HEL-S-90n
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
QPRT; Polyclonal Antibody; QPRT (Nicotinate-nucleotide Pyrophosphorylase [Carboxylating]; Quinolinate Phosphoribosyltransferase [Decarboxylating]) (AP); anti-QPRT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human QPRT.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Sequence Length
1524
Applicable Applications for anti-QPRT antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human QPRT, aa1-297 (AAH05060.1).
Immunogen Sequence
MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGILAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of QPRT expression in transfected 293T cell line by QPRT polyclonal antibody. Lane 1: QPRT transfected lysate (32.67kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of QPRT expression in transfected 293T cell line by QPRT polyclonal antibody. Lane 1: QPRT transfected lysate (32.67kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-QPRT antibody
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]
Product Categories/Family for anti-QPRT antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens quinolinate phosphoribosyltransferase, mRNA
NCBI Official Synonym Full Names
quinolinate phosphoribosyltransferase
NCBI Official Symbol
QPRT
NCBI Official Synonym Symbols
QPRTase; HEL-S-90n
NCBI Protein Information
nicotinate-nucleotide pyrophosphorylase [carboxylating]
Protein Family
NCBI Description
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Research Articles on QPRT
Similar Products
Product Notes
The QPRT (Catalog #AAA6391649) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The QPRT (Nicotinate-nucleotide Pyrophosphorylase [Carboxylating], Quinolinate Phosphoribosyltransferase [Decarboxylating]) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's QPRT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the QPRT for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "QPRT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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