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Fucose-1-phosphate guanylyltransferase (FPGT) Recombinant Protein | FPGT recombinant protein
Recombinant Human Fucose-1-phosphate guanylyltransferase (FPGT)
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NCBI and Uniprot Product Information
NCBI Description
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010]
Uniprot Description
Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.
Research Articles on FPGT
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Product Notes
The FPGT fpgt (Catalog #AAA1033389) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-594aa, Full length. The amino acid sequence is listed below: MAAARDPPEV SLREATQRKL RRFSELRGKL VARGEFWDIV AITAADEKQE LAYNQQLSEK LKRKELPLGV QYHVFVDPAG AKIGNGGSTL CALQCLEKLY GDKWNSFTIL LIHSGGYSQR LPNASALGKI FTALPLGNPI YQMLELKLAM YIDFPLNMNP GILVTCADDI ELYSIGEFEF IRFDKPGFTA LAHPSSLTIG TTHGVFVLDP FDDLKHRDLE YRSCHRFLHK PSIEKMYQFN AVCRPGNFCQ QDFAGGDIAD LKLDSDYVYT DSLFYMDHKS AKMLLAFYEK IGTLSCEIDA YGDFLQALGP GATVEYTRNT SNVIKEESEL VEMRQRIFHL LKGTSLNVVV LNNSKFYHIG TTEEYLFYFT SDNSLKSELG LQSITFSIFP DIPECSGKTS CIIQSILDSR CSVAPGSVVE YSRLGPDVSV GENCIISGSY ILTKAALPAH SFVCSLSLKM NRCLKYATMA FGVQDNLKKS VKTLSDIKLL QFFGVCFLSC LDVWNLKVTE ELFSGNKTCL SLWTARIFPV CSSLSDSVIT SLKMLNAVKN KSAFSLNSYK LLSIEEMLIY KDVEDMITYR EQIFLEISLK SSLM. It is sometimes possible for the material contained within the vial of "Fucose-1-phosphate guanylyltransferase (FPGT), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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