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Human ferredoxin reductase ELISA Kit | FDXR elisa kit

Human NADPH:adrenodoxin oxidoreductase, mitochondrial, FDXR ELISA Kit

Gene Names
FDXR; ADXR
Reactivity
Human
Synonyms
ferredoxin reductase; Human NADPH:adrenodoxin oxidoreductase; mitochondrial; FDXR ELISA Kit; mitochondrial (FDXR) ELISA kit; ADXR; adrenodoxin reductase; FDXR elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Assay Type
Quantitative Sandwich
Detection Range
0.625ng/ml-20ng/ml
Sensitivity
0.1ng/ml
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for FDXR elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of FDXR (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,837 Da
NCBI Official Full Name
NADPH:adrenodoxin oxidoreductase, mitochondrial isoform 3
NCBI Official Synonym Full Names
ferredoxin reductase
NCBI Official Symbol
FDXR
NCBI Official Synonym Symbols
ADXR
NCBI Protein Information
NADPH:adrenodoxin oxidoreductase, mitochondrial; AR; adrenodoxin reductase; adrenodoxin-NADP(+) reductase; ferredoxin--NADP(+) reductase
UniProt Protein Name
NADPH:adrenodoxin oxidoreductase, mitochondrial
UniProt Gene Name
FDXR
UniProt Synonym Gene Names
ADXR; AR; Adrenodoxin reductase; Ferredoxin reductase
UniProt Entry Name
ADRO_HUMAN

NCBI Description

This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

FDXR: Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Belongs to the ferredoxin--NADP reductase type 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Oxidoreductase; EC 1.18.1.6

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: protein binding; ferredoxin-NADP+ reductase activity; NADPH-adrenodoxin reductase activity

Biological Process: steroid metabolic process; cholesterol metabolic process; ubiquinone biosynthetic process; generation of precursor metabolites and energy; xenobiotic metabolic process; C21-steroid hormone biosynthetic process; steroid biosynthetic process; sterol metabolic process

Research Articles on FDXR

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Product Notes

The Human FDXR fdxr (Catalog #AAA9325284) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325284 ELISA Kit recognizes Human FDXR. It is sometimes possible for the material contained within the vial of "ferredoxin reductase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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